Prevention of Post-operative Nausea and Vomiting Following Laparoscopic Cholecystectomy

Background: Gallstone disease and its symptoms are frequently encountered in Indian population. Approximately, 80% of the gallstones are asymptomatic. Female sex, obesity, pregnancy, rapid weight loss, gallbladder stasis, and increasing age are a few risk factors for the development of gallstones. Materials and Methods: This study, “A study on the role of levosulpiride in prevention of post-operative nausea and vomiting (PONV) following laparoscopic cholecystectomy,” was conducted for 1 year (November 2014-October 2015), in the Department of Surgery, Acharya Shri Chander College of Medical Sciences and Hospital, Sidhra, Jammu. Patients admitted in the Department of Surgery for elective laparoscopic cholecystecytomy were enrolled in the study after fulfilling the eligibility criteria. The patients were allocated to 2 groups of 30 patients each on the basis of random sampling method. Result: Pre-operative administration of injection levosulpiride 25 mg in patients undergoing elective laparoscopic cholecystectomy surgeries under general anesthesia significantly reduces the incidence of PONV. Conclusion: It was hence seen to improve the quality of life in early stage of post-operative rehabilitation and also decreases the duration of hospital stay.